Description
Chemical formula – C21H25N3o2s
Drug class – atypical neuroleptics
Trade name – seroquel
USES – Antipsychotic drug.
- Used for treatment of schizophrenia, bipolar disorder, and major depressive disorder.
- Also used for sedating purpose.
Advantage – Also causes sedative effect.
Less extrapyramidal side effects.
100% bio availability
Side effects :
- Sleepiness
- Weight gain
- Dry mouth
- Postural hypotension
- Urinary retention
The drug is metabolized in liver , bio availability is 100%., excretion is through kidney and faeces, half life is 6 to 7 hours.
Dose-
400 to 800 mg tables orally.
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